For the first time, use a small amount, too much can cause oozing. It may take a few tries to find the right amount for your denture. Apply once a day for secure hold. If you need to apply more than once a day, seek advice from your dental care professional. Applying: 1. Apply Poligrip Fixative once a day to clean dry dentures, in short strips (as shown on diagram on pack), as shown. 2. Rinse mouth, press denture into place, hold firmly, then bite down to secure hold. Removing: 1. Swish mouth with warm water, then slowly remove denture. 2. Remove fixative residue from denture ; mouth with warm water ; soft brush.